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KMID : 1159320090110020127
Korean Journal of Vision Science
2009 Volume.11 No. 2 p.127 ~ p.135
Correlation of Central and Peripheral Corneal Thickness by Ages
Lee Hae-Jung

Jung Se-Ju
Lee Kyu-Byung
Jung Mi-A
Kim Hyung-Jin
Abstract
Purpose : To evaluate correlations between central and peripheral corneal thicknesses and between central and the thinnest corneal thicknesses by sex, sides and ages using Pentacam in Korean undergraduate students and elderly people.

Methods : 51 healthy eyes(male : 29, female : 22. average age : 22.50¡¾3.31 years) of undergraduate students and 39 healthy eyes of elderly people (male : 21, female : 18, average age : 54.26¡¾6.25 years) were recruited. We measured central, peripheral (3 mm away from the central cornea at 0¡Æ, 90¡Æ, 180¡Æ and 270¡Æ each) and the thinnest corneal thicknesses using Pentacam(Oculus Co.) and analyzed their correlations by sex, sides and ages.

Results : The average central corneal thickness was 555.98¡¾32.69 ¥ìm and peripheral corneal thicknesses were 681.72¡¾36.04 ¥ìm superiorly, 653.70¡¾38.04 ¥ìm nasally, 628.69¡¾35.18 ¥ìm inferiorly, and 624.26¡¾36.06 ¥ìm temporally in undergraduate students group. In elderly group, the average central corneal thickness was 543.69¡¾33.40 ¥ìm and peripheral corneal thicknesses were 649.97¡¾45.53 ¥ìm superiorly, 630.95¡¾39.65 ¥ìm nasally, 620.94¡¾37.09 ¥ìm inferiorly, and 614.28¡¾35.59 ¥ìm temporally. There were no significant differences between the sex(t = -0.3966, p = 0.69214) and between the sides(t = -0.41772, p = 0.67665), however we found a significant negative correlation with age. The inferotemporal quadrant is thinner than the superonasal quadrant. The thinnest points of right and left eyes were r = 0.69¡¾0.25 ¥ìm,¥è= 209.49¡Æ, 77/90 eyes and r = 0.57¡¾0.22 ¥ìm, ¥è= -41.57¡Æ, 78/90 eyes respectively. Increasing ages was associate with reduced the superonasal quadrant(r = -0.414, r =-0.254, r = -0.155 and r = -0.203 respectively). There was no correlation between the central corneal thickness and the thinnest corneal thickness.

Conclusion : Increasing age was associate with reduced peripheral corneal thicknesses in superonasal quadrant. The inferotemporal quadrant is thinner than the superonasal quadrant. The thinnest point was located in the inferotemporal quadrant. The information like age-related anatomic change would be useful for refractive surgery and etc.
KEYWORD
Scheimpflug photography, Pentacam, Central corneal thickness, Peripheral corneal thickness
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